[{"data":1,"prerenderedAt":117},["ShallowReactive",2],{"word-histone":3},{"source":4,"data":5,"quality_score":115,"lastmod":116},"static_word_details",{"lemma":6,"phonetic":7,"pos":9,"definition_zh":11,"usage_points":12,"collocations":34,"examples_basic":74,"examples_advanced":84,"common_mistakes":94,"synonyms_nuance":103,"diff_pairs":112,"word_family":114},"histone",{"us":8,"uk":8},"'histәun",[10],"名词","组蛋白是一种存在于真核细胞核中的碱性蛋白质，与DNA结合形成染色质结构，参与基因表达调控。",[13,20,27],{"title":14,"content":15,"examples":16},"句型搭配","histone通常作为名词使用，常见于描述其功能、修饰或与DNA的关系，如\"histone modification\"或\"histone binds to DNA\"。",[17,18,19],"histone modification","histone acetylation","histone binds to DNA",{"title":21,"content":22,"examples":23},"介词用法","histone常与介词\"in\"、\"of\"、\"with\"搭配，表示位置、所属或关联，例如\"histone in chromatin\"或\"modification of histone\"。",[24,25,26],"histone in chromatin","modification of histone","interact with histone",{"title":28,"content":29,"examples":30},"语域说明","histone是高度专业化的生物化学和分子生物学术语，主要用于学术、科研和医学领域，日常对话中极少使用。",[31,32,33],"histone research","histone in epigenetics","histone-related diseases",[35,43,51,57,63,68],{"type":36,"items":37},"verb",[38,39,40,41,42],"modify histone","acetylate histone","methylate histone","phosphorylate histone","bind to histone",{"type":44,"items":45},"adjective",[46,47,48,49,50],"core histone","linker histone","modified histone","acetylated histone","methylated histone",{"type":52,"items":53},"noun",[17,18,54,55,56],"histone methylation","histone code","histone variant",{"type":58,"items":59},"adverb",[60,61,62],"highly conserved histone","specifically modified histone","tightly bound histone",{"type":64,"items":65},"preposition",[24,66,67],"histone of nucleosome","histone with DNA",{"type":69,"items":70},"phrase",[71,72,73],"histone deacetylase inhibitor","histone modification patterns","histone-DNA interactions",[75,78,81],{"en":76,"zh":77},"In biology class, we learned that histone helps package DNA into chromosomes.","在生物课上，我们学到组蛋白帮助将DNA包装成染色体。",{"en":79,"zh":80},"The teacher explained how histone modifications can affect gene expression.","老师解释了组蛋白修饰如何影响基因表达。",{"en":82,"zh":83},"I read an article about histone and its role in cell division.","我读了一篇关于组蛋白及其在细胞分裂中作用的文章。",[85,88,91],{"en":86,"zh":87},"Recent studies show that histone acetylation is crucial for transcriptional activation in cancer cells.","最近研究表明，组蛋白乙酰化对癌细胞的转录激活至关重要。",{"en":89,"zh":90},"The research team investigated histone methylation patterns in neurodegenerative diseases.","研究团队调查了神经退行性疾病中的组蛋白甲基化模式。",{"en":92,"zh":93},"Histone deacetylase inhibitors are being developed as potential therapeutics for various cancers.","组蛋白去乙酰化酶抑制剂正在被开发为多种癌症的潜在治疗方法。",[95,99],{"wrong":96,"right":97,"explanation":98},"Histone is a type of DNA.","Histone is a protein that binds to DNA.","错误地将组蛋白误认为是DNA的一种；实际上，组蛋白是蛋白质，与DNA结合形成染色质。",{"wrong":100,"right":101,"explanation":102},"Histone can be found in all cells.","Histone is primarily found in eukaryotic cells.","错误地认为组蛋白存在于所有细胞中；实际上，组蛋白主要存在于真核细胞中，原核细胞通常没有组蛋白。",[104,108],{"word":105,"difference":106,"example":107},"chromatin","chromatin是DNA和组蛋白等蛋白质的复合物，而histone是其中的蛋白质组分；chromatin更强调结构整体。","Histone modifications alter chromatin structure to regulate gene expression.",{"word":109,"difference":110,"example":111},"nucleosome","nucleosome是染色质的基本单位，由DNA缠绕在组蛋白核心上形成；histone是构成nucleosome的蛋白质部分。","Each nucleosome contains eight histone proteins around which DNA is wrapped.",[113,105,109],"protein",[],70,"2026-01-09T04:59:40.790Z",1784307036301]